(The Monitor Daily, US) – For some patients suffering from life-threatening disease, an organ transplant may be the only option that can save their lives. In light of recent event, doctors will have to take more into account when assessing the recipient’s risk in the postoperative period. According to a new study, transplant recipients have an elevated risk of developing cancer, years after the transplant was finished.
On the 7th of January, a team of medical researchers from the University of Toronto has published a study in the JAMA journal of Oncology about how solid-organ recipients are at risk of developing a form of cancer.
The medical investigators have looked into 11.061 cases of organ transplantation procedures. In order to cover ever possible aspect of the dilemma, the investigators took into account all types of organs being harvested and implanted into compatible recipients.
During a period of 9 years, eligible recipients from Canada have received kidney, lung, heart and liver transplants. From 1991 all through 2010, the board of researchers looked into the medical records of 11.061 patients who underwent the transplantation procedure.
The team noted that transplant recipients have an elevated risk of developing cancer after they’ve managed to confront their conclusions with several databases from all over the country.
The study itself has been conducted from November 2013, through December 2015. In order to ascertain if there is a connection between transplantation and cancer, the medical examiner cross-referenced their finding with several official sources such as the Canadian Replacement Register, the Ontario Cancer Register and also with Ontario’s Office of General Registration.
From these databases, the team was also capable of ascertaining the rates of mortality and the risk of death from cancer.
According to their findings, during the multiple follow-ups from 1991 to 2010, 11.061 patients underwent a solid-organ transplantation procedure. From this group, 6516 patients received a new kidney, 929 patients received a heart transplant, 705 were subjected to lung transplantations and 2606 had a second chance of living a normal life after receiving a new liver.
Among other parameters taken into account were the average age, gender and pre-existent malignancies. According to their records, the patient’s average age was 49 years old and approximately 36.2 percent of organ recipients were females. To rule out anything that can tamper with the results, the medical scientists did not take into account the patient who had pre-existing neoplasms (approximately 1124 patients were diagnosed with neoplasm before the surgery).
The team’s conclusion is that transplant recipients have an elevated risk of developing cancer. The outcome of the study revealed over 3068 deaths over a 9-year timeframe, out of which nearly 603 cases were related to post-transplant malignancies.
By using the study’s conclusions, transplant teams can further hone their procedure concerning a patient’s post-surgery care.